Biodistribution and clearance of instilled carbon nanotubes in rat lung

Table 1 Quantification of Ni in rat's organs after instillation of MWCNT by intratracheal instillation.

	Treatment time (days)	1	7	30	90	180
LUNG	Lung after BAL	53 ± 12%	54 ± 10%	55 ± 8%	26 ± 6%	16 ± 9%
LUNG	Alveolar cells	10 ± 2%	24 ± 5%	14 ± 2%	12 ± 2%	-
LUNG	BALF	-	-	-	-	-
	Lymph nodes	-	-	28 ± 2%	-	-
	All other organs	-	-	-	-	-
	Total	63 %	78 %	97 %	38 %	16 %

- Non Detectable (< 2% of MWCNT instillated).
Groups of 6 rats were instillated by 100 μg of MWCNT and Ni was quantified by ICP-OES. Each value represents the mean ± SD of the percentage of Ni detected related to total Ni instillated (0.5 μg).

ISSN: 1743-8977