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Table 1 Quantification of Ni in rat's organs after instillation of MWCNT by intratracheal instillation.

From: Biodistribution and clearance of instilled carbon nanotubes in rat lung

  Treatment time (days) 1 7 30 90 180
LUNG Lung after BAL 53 ± 12% 54 ± 10% 55 ± 8% 26 ± 6% 16 ± 9%
LUNG Alveolar cells 10 ± 2% 24 ± 5% 14 ± 2% 12 ± 2% -
LUNG BALF - - - - -
  Lymph nodes - - 28 ± 2% - -
  All other organs - - - - -
  Total 63 % 78 % 97 % 38 % 16 %
  1. - Non Detectable (< 2% of MWCNT instillated).
  2. Groups of 6 rats were instillated by 100 μg of MWCNT and Ni was quantified by ICP-OES. Each value represents the mean ± SD of the percentage of Ni detected related to total Ni instillated (0.5 μg).
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