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Table 1 Hepatic mRNA expression levels of Sap, Saa1 and Saa3

From: Lack of acute phase response in the livers of mice exposed to diesel exhaust particles or carbon black by inhalation

Marker

0.9% NaCl i.p

LPS i.p.

Sap

0.00164 ± 0.00057

0.00408 ± 0.00055*

Saa1

0.00866 ± 0.00411

0.04081 ± 0.00423***

Saa3

0.00003 ± 0.00002

0.00360 ± 0.00087***

  1. Relative hepatic mRNA expression levels of acute-phase markers in mice measured 6 h after i.p. injection of 12.5 mg/kg LPS or 0.9% NaCl
  2. Messenger RNA expression levels were normalized to 18S rRNA. Mean ± SEM is shown (n = 4)
  3. *P < 0.05 versus 0.9% NaCl
  4. ***P < 0.001 versus 0.9% NaCl
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Particle and Fibre Toxicology

ISSN: 1743-8977

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