Table 1 Effect of Exposure to UFCB vs. FCB (High Dose) on pulmonary responses.

PMN (10⁶)

Control

1.5 ± 0.2

1.1 ± 0.1

1.0 ± 0.1

UFCB high

22.1 ± 0.8*

8.1 ± 0.3*

4.2 ± 0.7*

FCB high

15.5 ± 0.4*

5.7 ± 0.2*

3.3 ± 0.2*

LDH (U/l)

Control

49.3 ± 1.4

43.8 ± 0.8

45.1 ± 1.7

UFCB high

179.1 ± 6*

116.3 ± 4*

84.6 ± 2*

FCB high

135.3 ± 6*

88.6 ± 2*

71.9 ± 1*

Albumin (mg/ml)

Control

0.21 ± 0.1

0.12 ± 0.01

0.18 ± 0.02

UFCB high

0.48 ± 0.02*

0.31 ± 0.025*

0.32 ± 0.01*

FCB high

0.40 ± 0.01*

0.25 ± 0.01*

0.26 ± 0.01*

TNF-α (pg/ml)

Control

24.8 ± 0.5

28.2 ± 0.6

32.2 ± 0.6

UFCB high

45.3 ± 2*

50.4 ± 1*

60.1 ± 1*

FCB high

30.9 ± 0.8

34.3 ± 1

38.6 ± 0.9

MIP-2 (pg/ml)

Control

437.7 ± 14

497.2 ± 22

476.5 ± 22

UFCB high

544.1 ± 34*

727.8 ± 29*

615.2 ± 21*

FCB high

384.9 ± 22

485.8 ± 22

532.9 ± 22

IL-1β (pg/ml)

Control

58.1 ± 4

69.7 ± 5

70.5 ± 7

UFCB high

184.9 ± 10*

213.6 ± 8*

262.8 ± 9*

FCB high

78.6 ± 6

83.7 ± 9

115.7 ± 12

Zym. Stim. Chemi.

Control

3.14 ± .08

3.06 ± .09

3.22 ± .30

UFCB high

7.28 ± .13*

5.35 ± .12*

3.85 ± .55

FCB high

4.48 ± .10*

4.06 ± .04*

2.96 ± 41

NO Dep. Chemi.

Control

0.68 ± .05

0.52 ± .06

0.49 ± .07

UFCB high

4.2 ± .06*

3.6 ± .05*

2.4 ± .40*

FCB high

4.0 ± .04*

1.7 ± .05*

1.3 ± .04