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Table 2 The fold change and MS results of the differently expressed proteins

From: SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cells

Spot no. Protein ID Fold change (dosage:10 μg/mL) NCBI database no. Mr (Da)/PI Protein score Coverage rate* %
   Micro-sized SiO 2 30-nm SiO 2 15-nm SiO 2     
Oxidative stress-associated proteins
717 peroxiredoxin 6 -1.21 -.199 -2.11 gi|4758638 25019.2/6 413 58
796 peroxiredoxin 1 -1.20 -1.44 -1.63 gi|4505591 22096.3/8.2 397 54
806 peroxiredoxin 2 isoform a -1.33 -1.62 -1.88 gi|32189392 21878.2/5.66 375 47
1019 thioredoxin -1.22 -2.59 -2.44 gi|50592994 11729.7/4.82 161 45
779 GSTP1 -1.31 -1.84 -1.95 gi|4699783 23325/4.55 253 52
Cytoskeleton-associated proteins
416 gelsolin-like capping protein (CAPG) -1.46 -1.92 -2 gi|63252913 38474.5/5.82 168 29
248 keratin 8 -1.37 -1.31 -1.35 gi|33875698 55787.2/5.62 640 53
760 keratin 19 1.89 4.35 4.06 gi|34783124 45587/5.11 402 51
217 keratin 4 (408 AA) -- 1.31 1.20 gi|34073 57249.8/6.25 289 44
Molecular chaperones
797 cyclophilin -1.45 -1.90 -1.87 gi|4758950 23727.5/9.42 310 67
922 PPIA -- -1.45 -1.37 gi|48145531 17986.9/7.68 71 44
Metabolism-associated proteins
307 enolase 1 variant -1.30 -1.92 -2.17 gi|62896593 47111.3/7.01 265 50
688 phosphoglycerate mutase (PGAM) -1.21 -1.86 -1.79 gi|89035672 28831.8/6.67 240 43
132 ATP5A1 -1.27 -1.79 -1.79 gi|4757810 59713.6/9.16 444 50
682 Chain, CCarbonic Anhydrase Ii -1.48 -2.34 -2.36 gi|443135 28718.7/6.63 338 59
Apoptosis and tumor-associated proteins
436 maspin -1.36 -1.60 -1.70 gi|4505789 42111.4/5.72 219 33