Table 1 Relative organ weights for male rats after 90-day oral administration of silver nanoparticles (mean ± S.D., n≥9)

0

30

125

500

Testis (Left)

0.47 ± 0.02

0.48 ± 0.03

0.49 ± 0.02

0.51 ± 0.01*

Testis (Right)

0.47 ± 0.02

0.48 ± 0.02

0.48 ± 0.02

0.49 ± 0.02

Spleen

0.21 ± 0.03

0.21 ± 0.01

0.22 ± 0.01

0.20 ± 0.02

Liver

2.96 ± 0.10

2.91 ± 0.16

2.92 ± 0.09

2.87 ± 0.11

Pituitary gland

0.002 ± 0.001

0.003 ± 0.001

0.005 ± 0.006

0.004 ± 0.003

Adrenal gland (Left)

0.011 ± 0.006

0.007 ± 0.002

0.008 ± 0.001

0.009 ± 0.003

Adrenal gland (Right)

0.008 ± 0.001

0.007 ± 0.001

0.008 ± 0.001

0.009 ± 0.002

Prostate

0.13 ± 0.06

0.16 ± 0.05

0.15 ± 0.04

0.16 ± 0.05

Lungs

0.42 ± 0.02

0.41 ± 0.04

0.42 ± 0.03

0.43 ± 0.03

Brain

0.62 ± 0.02

0.61 ± 0.03

0.62 ± 0.02

0.63 ± 0.02

Heart

0.27 ± 0.02

0.26 ± 0.02

0.27 ± 0.01

0.26 ± 0.02

Thymus

0.10 ± 0.02

0.10 ± 0.02

0.11 ± 0.02

0.10 ± 0.02

Kidney (Left)

0.28 ± 0.01

0.28 ± 0.02

0.29 ± 0.01

0.28 ± 0.01

Kidney (Right)

0.29 ± 0.02

0.28 ± 0.02

0.29 ± 0.01

0.29 ± 0.01