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Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

Figure 6

Cytokine accumulation in bronchoaleolar lavage fluid of C57BL/6 mice following aspiration of CNF, Crocidolite Asbestos, or SWCNT. A: TNF-α; B: MCP-1; C: IL-6; D: IL-12p70; E: IFN-γ; F: IL-10. Open columns - exposure with SWCNT (40 μg/mouse); gray columns - exposure with CNF (120 μg/mouse); black columns - exposure with crocidolite asbestos (120 μg/mouse). Mice were exposed via pharyngeal aspiration to the indicated doses. Animals were sacrificed 1, 7, and 28 days post exposure. Means ± SE (n = 6 mice per group).*p < 0.05 vs. control (PBS) exposed mice, βp < 0.05 vs. mice exposed to asbestos.

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