Endpoints measured in MDM. Several endpoints in MDM were analysed after exposure to different functionalized and pre-coated MWCNTs. a. Cytotoxicity (lactate dehydrogenase release), b. Reactive oxygen species, c. Intracellular glutathione, d. Tumor necrosis factor-α. (For an optimized representation of group comparisons the same data are visualized in two diagrams. Values are shown relative to the medium control which corresponds to a mean concentration of 87.1 pg/ml), e. Necrosis, f. Apoptosis (For an optimized representation of group comparisons the same data are visualized in three diagrams.). Endpoints were assessed after 24 h exposures apart from ROS (B), which was assessed after 1 h. Experiments have been performed in 3 to 5 repetitions. Data shows mean values ± standard deviation (SD). Different groups were compared by ANOVA and Bonferroni post hoc tests (* = p < 0.05, ** = p < 0.01).