Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

Table 1 Characteristics of non-crystalline silica particles

Silica particles	TEM (own measurements)	Surface area (cm²/mg)	ζ-potential (mV) (in water)
Silica (50 nm, Si50)	64 ± 7.7 nm	650	−29,8
Silica (500 nm, Si500)	369 ±19.7 nm	90	−37,2
Fumed silica (Aerosil)	~20 nm	1880	−23,9
Fused silica (Suprasil)	^*500 nm −10 μm	^*23	^**-34,4

The characteristics (TEM; surface area, and ζ-potentials) of two different mono-disperse non-crystalline (amorphous) silica particles with different nominal size, and two different poly-disperse amorphous silica particles are presented. The TEM, ζ-potentials (in water), and the particle surface areas were measured as described in Material and Methods. ^* The TEM and the surface area of the fused particles were measured before wet sedimentation and include larger particles. ^**The ζ-potential was measured for the fused particles after wet sedimentation.

ISSN: 1743-8977