Figure 3
From: Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint
DNA strand breaks in hepatic tissue. DNA strand breaks in liver tissue from mice exposed to 0, 18, 54 or 162 μg of NanoTiO2 (A) or Printex 90 (B) or 0 or 486 μg of Indoor-R or Indoor-NanoTiO2 (C). The statistical analysis for Printex 90 has been described previously [19]. The increased level of DNA strand breaks of Indoor-R is considered an artifact due to 1) a low plate control and the normalization procedure and 2) the unusual kinetic of DNA damage over time. *, **, ***: Statistically significant compared to control mice at the 0.5, 0.01 and 0.001 level, respectively.