Skip to main content
Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Nitric oxide and superoxide mediate diesel particle effects in cytokine-treated mice and murine lung epithelial cells — implications for susceptibility to traffic-related air pollution

Figure 4

Superoxide anion production in DEP-exposed cells. (A) DHE fluorescence (red) oxidation by O2˙- in DEP-exposed cells (25 μg/cm2 × 2 h). DNA was counter-stained with DAPI (blue) and is representative of two independent experiments. (B) XdH mRNA expression of saline- and DEP-exposed cells (25 μg/cm2 × 24 h). Data are expressed as the mean fold-increase (±SEM) over control cells and is representative of three independent experiments. (C) Activity of cytosolic superoxide dismutase (CuZn SOD) and mitochondrial (Mn SOD) SOD from DEP-exposed cells (25 μg/cm2 × 24 h). Data are expressed as the mean (± SEM) activity of SOD and is representative of three independent experiments. Significance ( p < 0.05) is indicated by: * vs. control.

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us