Figure 3
Microarray analysis of BEAS 2B cells in response to silica particle exposure (24 h). (A) Total number of significant gene changes (p < 0.05) with a cut-off of ≥ 2.0-fold change in mRNA compared to unexposed controls in BEAS 2B exposed for 24 h (total number of gene changes). Gene ontology analysis of BEAS 2B exposed to (B) Cristobalite at 75 × 106μm2/cm2, (C) 150 × 106μm2/cm2 and (D) amorphous silica at 150 × 106μm2/cm2. Positive values represent number of genes up-regulated (Black bars) and negative values represent number of genes down-regulated (white bars) (N = 3).