Table 2 Parameters and dose metrics of administered ¹⁹⁸ AuNP; additionally ¹⁹⁸ AuNP doses in the fetuses 24 hours after intravenous injection

AuNPs, core diameter (nm)

1.4

18

80

Hydrodynamic diameter (nm) after neutron irradiation

2.9^#

21^$

94^$

(Ph₂PC₆H₄SO₃Na); ligand molecules/NP^#

12

1.5 ¿ 2 x 10³⁺

3 - 4 x 10⁴⁺

Specific ¹⁹⁸Au radioactivity (GBq/g)

19

31

8.3

Isotope ratio of ¹⁹⁸Au to stable ¹⁹⁷Au

4 10^?8

6 10^?8

1.2 10^?6

Ratio of ¹⁹⁸Au per AuNP

2 10^?6

1 10^?2

19

pH Value of suspension

5.6

6.4

5.4

Zeta potential (mV)

?20.0?±?2.4

?22.8?±?3.1

?27.1?±?1.3

Administered mass of AuNP (?g) per rat

5.2?±?0.6

3.2?±?0.9

26.5?±?5.0

Administered number of AuNP per rat

1.9?±?0.2 x 10¹⁴

5.5?±?1.5 x 10¹⁰

5.2?±?1.0 x 10⁹

AuNP mass (ng) retained in fetuses

30

0.12

< 0.1*

Number of AuNP retained in fetuses

1.2 x 10¹¹

2.4 x 10⁶

< 2 x 10⁴*