Table 1 Incidences of malignant mesotheliomas, mean survival times of morbid mesothelioma-bearing rats, and first day of mesothelioma detection
Substance | Length (μm) WHO fibers* | Diameter (μm) WHO fibers* | Dose WHO fibers* 109per rat (actual##) | No. of rats | Rats with mesothelioma | Mean survival time of mesothelioma-bearing rats (days) | Month of first detection of a morbid mesothelioma-bearing rat | Final month** |
|---|---|---|---|---|---|---|---|---|
Medium control | - | - | - | 50 | 1 (2%) | 739 | 24 | 24 |
MWCNT A low | 8.57 ± 1.51 | 0.085 ± 1.60 | 0.48 | 50 | 49 (98%) | 213 | 5 | 9 |
MWCNT A high | 2.39 | 50 | 45 (90%) | 194 | 5 | 8 | ||
MWCNT B low | 9.30 ± 1.63 | 0.062 ± 1.71 | 0.96 | 50 | 46 (92%) | 294 | 6 | 13 |
MWCNT B high | 4.80 | 50 | 45 (90%) | 207 | 5 | 9 | ||
MWCNT C low | 10.24 ± 1.64 | 0.040 ± 1.57 | 0.87 | 50 | 42 (84%) | 415 | 10 | 18 |
MWCNT C high | 4.36 | 50 | 47 (94%) | 265 | 6 | 11 | ||
MWCNT D low | 7.91 ± 1.40 | 0.037 ± 1.45 | 1.51 | 50 | 20 (40%) | 666 | 20 | 24 |
MWCNT D high | 7.54 | 50 | 35 (70%) | 585 | 11 | 24 | ||
Long amosite asbestos | 13.95 ± 2.10 | 0.394 ± 1.83 | 0.14 | 50 | 33 (66%) | 623 | 14 | 24 |