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Table 3 Associations between inorganic soluble chemical constituents, polyaromatic hydrocarbons (PAHs) and microbes in indoor and outdoor air PM separately and the inflammatory and cytotoxic response markers in mouse macrophages after exposure to three different doses of particles (50, 150 and 300 μg/ml) for 24 h

From: Role of microbial and chemical composition in toxicological properties of indoor and outdoor air particulate matter

Indoor

  

n

MTT

PI

SubG1

TNFα

MIP2

n

MTT

PI

SubG1

TNFα

MIP2

PC1

A1

24

.546**

.457*

0.302

.722**

.713**

24

.912**

.735**

−0.094

.892**

.921**

 

Ca

24

.771**

.637**

.682**

.543**

.603**

24

.856**

.733**

0.209

.730**

.777**

 

Fe

21

.640**

.548*

0.287

.884**

.830**

24

.901**

.719**

−0.104

.882**

.909**

 

K

24

.809**

.777**

.737**

.488*

.499*

24

.785**

.726**

0.285

.590**

.597**

 

Mg

24

.589**

.555**

.528**

.453*

.477*

24

.928**

.767**

−0.026

.887**

.915**

 

Na

24

.661**

.646**

.599**

.484*

.514*

24

.888**

.645**

0.13

.651**

.695**

 

Ni

24

.510*

.540**

.507*

0.306

0.307

24

.623**

.504*

0.369

0.307

0.311

PC2

SO4

24

0.273

.467*

.583**

−0.357

−0.298

24

−0.12

−0.164

0.403

.-543**

.-529**

 

NO3

24

.776**

.886**

.831**

0.27

0.317

21

0.316

0.152

0.373

−0.001

0.122

 

V

24

.636**

.667**

.756**

0.092

0.115

24

.567**

.407*

.499*

0.222

0.292

 

Zn

24

.551**

.547**

.686**

0.082

0.143

24

.441*

.415*

.476*

0.116

0.139

 

TotalPAH

24

0.344

.414

.623**

−0.326

−0.229

24

−0.269

.-435*

.475*

.-675**

.-610**

PC3

C1

24

.863**

.724**

.683**

.697**

.702**

24

.551**

0.306

0.115

.462*

.559**

 

F

21

.927**

.888**

.777**

.665**

.656**

18

0.463

0.254

.553*

0.019

0.101

 

Cu

24

.497*

.570**

.583**

0.184

0.211

24

.810**

.763**

0.299

.629**

.641**

PC4

Universal bacterial assay

24

.820**

.671**

.674**

.567**

.599**

24

.847**

.589**

−0.188

.831**

.843**

Other

Genotoxic PAH

24

0.25

0.326

.557**

.-423*

−0.332

24

−0.269

−0.392

.477*

.-685**

.-636**

 

EU PAH

24

0.131

0.22

.497*

.-533**

.-444*

24

−0.316

−0.353

.489*

.-710**

.-683**

 

Penicillium sp./Aspergillus sp.

24

.666**

.565**

.571**

.472*

.475*

24

.788**

.659**

−0.045

.778**

.792**

 

Cladosporidium cladosprioides

24

.787**

.685**

.483*

.820**

.816**

21

.806**

.666**

0.197

.803**

.766**

 

Streptomyces sp.

24

.550**

.650**

.609**

0.083

0.065

15

.700**

.621*

.668**

0.232

0.361

 

Mycobacterium sp.

24

.843**

.701**

.682**

.597**

.623**

15

.879**

.900**

0.479

.957**

.982**

  1. The values are Spearman correlation coefficients (ρ), (** p < 0.01, * p < 0.05).
  2. Genotoxic PAH compounds according to WHO (1998).
  3. EU PAH compounds according to the EU Directive 2014/107/EC.
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Particle and Fibre Toxicology

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