Table 2 Particulate matter effects on gene expression of angiotensin and bradykinin systems in the heart. Semi-quantitative expression results for angiotensin-receptor type-2 (At2r), Bradykinin receptor type-1 (B1r) and kallikrein (Klk-1) enzyme after acute and subchronic exposures

Group

FA

CP

FP

UFP

Gene

At2r

1

1

1

1

(0.8-1.2)

(1-1.1)

(0.9-1.1)

(0.5-1)

Ace

1

1.6 *

1.1

1.7 *

(0.9-1.1)

(1.4-1.8)

(0.9-1.3)

(1.1-2.1)

B1r

1

1.7 *

2.2 *

1.9 *

(0.8-1.3)

(1.4-2.2)

(2.1-2.6)

(1.3-2.4)

Klk-1

1

1.2

1.6 *

1.4 *

(0.8-1.2)

(1-1.5)

(1.4-1.9)

(1.2-1.5)

Group

FA

CP

FP

UFP

Gene

At2r

1

0.97

0.92

0.71 *

(0.96-1.03)

(0.97-1.05)

(0.72-0.9)

(0.7-0.8)

Ace

1

1

1

0.9

(0.9-1.1)

(0.9-1.1)

(0.9-1.3)

(0.8-1)

B1r

Klk-1

1

1.1

1.2 *

1.1

(0.9-1.1)

(0.9-1.2)

(1.19-1.22)

(1-1.3)