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Table 2 Cerium concentration at 28 days post-instillation of uncoated or silica-coated CeO2 NPs

From: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

  CeO2 Silica-coated CeO2
  ng/g ± SE ng/g ± SE
Lungs 136836.67 ± 4084.19 95193.25 ± 1766.39 *
Liver 59.35 ± 10.19 33.10 ± 2.78 *
Bone 38.13 ± 5.14 21.97 ± 2.87 *
Cecum 33.62 ± 10.95 24.15 ± 6.58
Large intestine 28.11 ± 8.94 24.33 ± 8.01
Bone marrow 16.55 ± 2.55 9.44 ± 1.05 *
Spleen 13.90 ± 6.21 3.83 ± 0.59
Stomach 12.77 ± 2.09 16.82 ± 8.64
Kidneys 10.40 ± 1.13 5.52 ± 0.35 *
Small intestine 10.14 ± 1.49 7.94 ± 2.20
Heart 1.95 ± 0.54 0.21 ± 0.08 *
Testes 0.54 ± 0.08 0.13 ± 0.04 *
Skeletal muscle 0.46 ± 0.21 0.20 ± 0.09
Brain 0.43 ± 0.24 0.15 ± 0.11
Skin 0.38 ± 0.08 0.16 ± 0.01 *
Plasma 0.14 ± 0.09 0.04 ± 0.04
RBC 0.04 ± 0.04 0.08 ± 0.06
  1. Data are mean ± SE ng/g cerium concentration, n = 5/group
  2. Ce concentration was estimated (ng/μCiNPs x μCi/gtissue)
  3. *P < 0.05, CeO2 vs. silica-coated CeO2