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Table 3 Concentrations of half-maximal basophil activation (C50) of free allergen versus AuNP-allergen conjugates for all donors tested. In conjugates the given values refer to the amounts of coupled allergen. Donors displaying X were tested but could not be statistically evaluated

From: Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses

  C50 [ng/ml]
Donor Bet v 1 AuNP-Bet v 1 conjugates Der p 1 AuNP-Der p 1 conjugates Phl p 5 AuNP-Phl p 5 conjugates
1 X X X X X X
2 178 1 4 2 X X
3 444 51 186 55 X X
4 52 13 27 1 16 19
5 287 548 58 20 X X
6 78 107 --- --- 1 1
7 48 43 --- --- 29 12
8 2 2 --- --- 65 77
9 12 89 --- --- --- ---