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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: An acetyl-L-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminum oxide nanoparticles

Fig. 3

qRT-PCR validation of the expression levels of modulated mitochondria-related mRNA. a Mitochondria-related gene expression level in HBE cells treated with 50, 100, 250 or 500 μg/ml Al2O3 NPs. Gene expression is regulated in a dose-dependent manner b: Gene expression level of lung tissues in mice exposed to Al2O3 NPs through inhalation. Gene expression is regulated in a dose-dependent manner. c Except NDUFA4, fold change of modulated genes in cells treated with 100 μg/ml Al2O3 NPs are consistent with array data

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