Table 4 Body weight gain and relative organ weight (%) after IV administration of 10 mg silver/kg. Data are expressed as means ± SD
Group | n | Body weight gain | Spleen | Liver | Lung | Kidney | Brain |
|---|---|---|---|---|---|---|---|
Control | 3 | −3.3 ± 5 | 0.45 ± 0.1 | 6.61 ± 0.8 | 0.66 ± 0.0 | 1.80 ± 0.2 | 1.77 ± 0.1 |
10 nm AgNP | 6 | −12.1 ± 4.1* | 0.67 ± 0.0* | 7.23 ± 1.1 | 0.76 ± 0.1 | 1.75 ± 0.1 | 1.81 ± 0.2 |
40 nm AgNP | 6 | −1.3 ± 2.8++ | 0.54 ± 0.1++ | 6.87 ± 0.6 | 0.65 ± 0.1 | 1.79 ± 0.3 | 1.78 ± 0.1 |
100 nm AgNP | 6 | −0.1 ± 5.0++ | 0.40 ± 0.1++ | 6.97 ± 0.2 | 0.63 ± 0.1 | 1.80 ± 0.1 | 1.65 ± 0.1 |
AgAc | 3 | −6.3 ± 3.3 | 0.47 ± 0.0+ | 6.99 ± 0.0 | 0.80 ± 0.1 | 1.92 ± 0.2 | 1.78 ± 0.2 |