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Table 5 Percentage of recovered silver dose in mice after IV administration of 10 mg silver/kg. Data are expressed as means ± SD

From: Tissue distribution and acute toxicity of silver after single intravenous administration in mice: nano-specific and size-dependent effects

Group

n

Spleen

Liver

Lung

Kidney

Brain

10 nm AgNP-CT

3

6.6 ± 1.2

52.0 ± 4.7

4.2 ± 1.1

0.5 ± 0.1

0.056 ± 0.015

10 nm AgNP-PVP

3

5.3 ± 1.0

41.1 ± 2.3

1.5 ± 1.2

0.4 ± 0.1

0.049 ± 0.016

40 nm AgNP-CT

3

3.6 ± 1.1

46.1 ± 2.5

0.5 ± 0.1

0.1 ± 0.1

0.037 ± 0.007

40 nm AgNP-PVP

3

3.1 ± 1.1

45.5 ± 1.9

0.3 ± 0.1

0.2 ± 0.0

0.035 ± 0.009

100 nm AgNP-CT

3

2.7 ± 0.4

36.7 ± 0,3

0.5 ± 0.1

0.1 ± 0.0

0.029 ± 0.004

100 nm AgNP-PVP

3

2.5 ± 0.6

45.7 ± 1.1

0.2 ± 0.0

0.1 ± 0.0

0.028 ± 0.003

AgAc

3

0.6 ± 0.2

42.6 ± 4.5

0.3 ± 0.1

2.4 ± 0.6

0.064 ± 0.011