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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

Fig. 3

The distribution of pathway BMD-median values is influenced by post-exposure time. Distributions of pathway BMD-median values for NM-401 (top), NRCWE-026 (center), and Mitsui-7 (bottom). Pathways were only considered in this analysis if they were significant (P < 0.05) with five or more DEGs associated with them and if they had five or more molecules with goodness-of-fit P value > 0.1 and BMD/BMDL ratios < 10. Overlain table indicates the median BMD(L) across all pathways for each time-point

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