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Table 3 Relevant in vitro dose (RID) functions for nCeO2, amsCeO2, and aSiO2 nanoparticles when dispersed in FGM

From: Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating

Nanomaterial

M

N

SA

RIDM

RIDN

RIDSA

nCeO2 Low dose

0.01

2.08E-09

3.63E-16

0.01

1.08E-16

1.88E-23

nCeO2 High dose

0.40

4.25E-01

4.53E-01

0.36

2.20E-08

2.35E-08

amsCeO2 Low dose

0.01

6.82E-10

3.90E-17

0.01

5.88E-17

3.37E-24

amsCeO2 High dose

0.40

3.10E-01

2.41E-01

0.39

2.68E-08

2.08E-08

aSiO2 Low dose

0.01

6.56E-11

9.69E-05

0.01

3.11E-18

4.60E-12

aSiO2 High dose

0.40

1.10E + 00

1.62E + 06

0.39

5.20E-08

7.68E-02

  1. Delivered dose values based on delivered ENM mass (M), delivered particle number (N), and delivered surface area (SA) for either a high (0.57 μg/mL, equivalent to 0.2 μg/cm2 for this study) or low (0.017 μg/mL, 0.006 μg/cm2) dose
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Particle and Fibre Toxicology

ISSN: 1743-8977

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