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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary exposure

Fig. 2

Characterization of uncoated MWCNTs (U-MW), ZnO-coated MWCNT (Z-MW), and ZnO nanoparticles (ZnO NP). a Length of ZnO coated MWCNT decreased post sonication as measured by TEM. b MWCNT aggregate size decreased with ZnO coating. For the data in panels A and B, The mean is represented as a + and the median as a solid line. For box and whisker plots the box represents the range from the 25th to 75th percentile. Significance is represented as * without a bracket as compared to the control, * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001. c Time course of Zn+2 ion concentration generated from Z-MWCNT or ZnO NP in serum free media. Zn+2 concentration was measured in serum-free medium in the absence of cells using 200 μg/ml of nanomaterial as described in Methods. Data are the mean and SEM of 5 measurements at each time point. d H2O2 production in serum free media was significantly increased by Z-MWCNT (Z-MW), but not U-MWCNT (U-MW), compared to control. Data are the mean and SEM of 6 replicate measurements. *P < 0.05 compared to control

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