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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Dietary silver nanoparticles can disturb the gut microbiota in mice

Fig. 4

Weighted UniFrac distance analysis. a Principal Coordinates Analysis (PCoA) is based on the UniFrac distance matrix generated from all samples of each group of Ag NP dose (0, 46, 460, 4600 ppb). Control samples tend to form a cluster separated from Ag NP treated samples, highlighting the proximity and the similarity of their microbial composition within groups and the significant effect of the treatment. b The boxplot of the UniFrac distances shows that distances between treated samples and the averaged control profile increasing with the dose. This dose-dependent effect was confirmed by the permutational multivariate analysis of variance (ADONIS) of the weighted UniFrac distance matrix by assuming a linear trend effect of the Ag NP dose on the microbial structure (p < 0.001, n = 5)

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