Skip to main content

Advertisement

Table 4 Fetal metabolism at 28 dpc for the second generation

From: Maternal exposure to diluted diesel engine exhaust alters placental function and induces intergenerational effects in rabbits

Variable Number of fetuses Median [Q1; Q3] Fully adjusted linear model
C E C E β value CI P-value
Glycemia (mmol/L) 14 12 1.400 [1.175; 1.765] 1.730 [1.618; 2.070] 0.257 [−0.173;0.687] 0.275
Insulin (mUI/L) 14 12 4.170 [1.990; 10.09] 2.545 [1.703; 3.765] −2.965 [−6.245;0.315] 0.111
Total cholesterol (mmol/L) 15 12 2.550 [2.180; 2.640] 1.890 [1.800; 2.240] −0.416 [−0.648;-0.183] 0.008**
HDL cholesterol (mmol/L) 15 12 0.730 [0.685; 0.790] 0.650 [0.590; 0.750] −0.071 [−0.156;0.015] 0.143
Non-HDL cholesterol (mmol/L) 15 12 1.730 [1.480; 1.898] 1.280 [1.150; 1.480] −0.348 [−0.54;-0.156] 0.007**
Triglycerids (mmol/L) 15 12 0.540 [0.440; 0.598] 0.680 [0.610; 0.730] 0.176 [0.062;0.289] 0.015*
ASAT (UI/L) 15 10 107.5 [97.00; 116.0] 110.0 [95.00; 137.0] 15.66 [−14.542;45.863] 0.335
Creatinine (μmol/L) 15 12 72.00 [66.00; 76.25] 72.00 [67.00; 77.00] 0.082 [−6.745;6.909] 0.982
Urea (mmol/L) 15 12 4.650 [3.950; 5.200] 3.700 [3.500; 4.600] −0.303 [−1.779;1.174] 0.696
  1. The effects of exposure to engine diesel exhaust during grand-mother pregnancy on second-generation fetuses were estimated using a linear model with random effect of dam adjusted for litter size, fetal sex and the position of the fetus in the horn. All data are expressed as median [Q1;Q3] (*p < 0.05, **p < 0.01, compared with control group)