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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter

Fig. 9

Scatter plots of key corresponding in vitro and in vivo combined particle potency estimates βR CELLS (in vitro assays) with βT BALB/c (in vivo cell counts and biochemical endpoints) (a); βI-V CELLS (in vitro cytokines) with βI BALB/c (in vivo cytokines) (b) and integrated particle potency estimates, Iβ CELLS (averaged in vitro assays and cytokines) with Iβ BALB/c(average of in vivo cell counts, biochemical endpoints and cytokines) (c). Pearson correlation coefficients and p-values (1-tailed) are presented for correlations of all particles (dashed grey line) and particles excluding CRI (solid black line)

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