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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

Fig. 9

Lysosomal damage, cathepsin B release and IL-1β production in THP-1 cells. THP-1 cells were incubated with 50 μg/mL CoO or La2O3 nanoparticles for 6 h. Then cells were stained with Magic Red-labeled cathepsin B substrate and visualized by confocal microscopy (a). IL-1β production was assessed by ELISA after THP-1 cells were treated with 0–100 μg/mL CoO or La2O3 nanoparticles for 24 h. (b)

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