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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo

Fig. 2

Effects of ZnO NPs on cellular ROS and the expression of HIF-1α-related proteins in HEK-293 cells. a ROS generation in HEK-293 cells treated with ZnO NPs for 1, 3 or 5 h and with DCFH-DA for an additional 30 min. The fluorescence in the cells was immediately analyzed using a fluorescence microplate reader. b Western blotting for HIF-1α, PAI-1 and CTGF in HEK-293 cells. The cells were treated with ZnO NPs for 24 h

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