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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation

Fig. 6

Myofibroblast differentiation. WT and Opn KO mice were exposed to DM or 40 μg MWCNTs for 7 or 28 days. (a) Immunofluorescence of myofibroblast marker α-SMA on mouse lung sections. (b) Immunofluorescence of myofibroblast marker PDGFR-β on mouse lung sections. In (a) and (b), red indicates positive staining, and blue indicates nuclear staining (scale bar: 20 μm). Relative intensity of positive staining was measured and presented as mean ± SD (n = 4)

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