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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats

Fig. 3

Nanoparticle exposure-related lung burden. Rats were exposed to clean air, 0.1, 0.3, 1.0 or 3.0 mg/m3 CeO2 or 50.0 mg/m3 BaSO4 nanoparticles for up to 90 days. Ce and Ba contents were measured in explanted lungs at exposure day one and 28 as well as post-exposure day one (d 91), 28 (d 118) and 90 (d 180). a Mean total Ce/Ba content (insoluble + soluble fraction) ± SD, n ≤ 5; b Mean total Ce/Ba content (insoluble + soluble fraction) normalized to the related initial nanoparticle concentration. Ba contents in the clean air control were at the detection limit and are therefore not shown. The mean insoluble fraction was <5% of the total content

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