Fig. 10From: Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cellsInduction of apoptosis (a) and necrosis (b) after treatment with CuO NP, CuO MP and CuCl2. BEAS-2B cells were treated with the different copper compounds for 48 h. Shown are mean values of four determinations derived from two independent experiments + SD. Statistically significant different from control: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 (ANOVA-Dunnett’s T test). 20 μg/mL CuO are equal to 252 μM Cu2+. n.d.: not determinedBack to article page