Skip to main content
Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells

Fig. 2

Cellular copper uptake and intracellular copper distribution after treatment with CuO NP, CuO MP and CuCl2. Copper content was determined in the soluble fraction of the total cell (a), the cytoplasm (b) and the nucleus (c) in BEAS-2B cells after 24 h treatment with the different copper compounds via GF-AAS. Shown are mean values of three independent experiments + SD ((a) and CuO NP (b,c)), mean values of six independent experiments + SD (10 μg/mL CuO NP (b,c)) or mean values of two independent experiments + R/2 (CuO MP and CuCl2 (b, c)). Statistically significant different from control: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 performed in case of (a) and CuO NP (b, c) (ANOVA-Dunnett’s T test). 20 μg/mL CuO are equal to 252 μM Cu2+. n.d.: not determined

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us