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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Imipramine blocks acute silicosis in a mouse model

Fig. 8

Protective effect of IMP on collagen accumulation during co-administration study. Mice were exposed to silica or vehicle weekly for the first four weeks, while receiving IMP or PBS by osmotic pump for entire six week duration. Hydroxyproline in lungs was measured as an indicator of collagen accumulation. n ≥ 3 mice per treatment condition

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Particle and Fibre Toxicology

ISSN: 1743-8977

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