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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

Fig. 1

Adverse Outcome Pathway (AOP) for the development of MWCNT-induced lung fibrosis. Graphical depiction of the key events that describe the progression from inhalation exposure to MWCNTs to the development of pulmonary fibrosis. The figure highlights the molecular initiating event (MIE), key events (KE), associative events (AE), and the adverse outcome (AO)

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