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Table 5 Percentage of Ni in bronchoalveolar lavage fluid (BALF) per Ni in total lung post-administration

From: Kinetics and dissolution of intratracheally administered nickel oxide nanomaterials in rats

   (Ni in BALF) / (Ni in lung and BALF)
   3 days after i.t. 28 days after i.t. 91 days after i.t.
NiO A 0.57 mg/kg-bw 2.4% ± 1.2% 0.84% ± 0.11% 1.2% ± 0.24%
1.9 mg/kg-bw 0.59% ± 0.043% 0.89% ± 0.043% 0.60% ± 0.041%
5.8 mg/kg-bw 0.79% ± 0.52% 2.5% ± 0.70% 0.89% ± 0.48%
NiO B 0.45 mg/kg-bw 3.0% ± 0.88% 31% ± 13% 76% ± 17%
1.5 mg/kg-bw 4.0% ± 1.0% 19% ± 5.0% 38% ± 2.9%
4.0 mg/kg-bw 2.8% ± 0.82% 8.9% ± 1.8% 22% ± 5.8%
NiO C 0.47 mg/kg-bw 1.7% ± 0.72% 3.2% ± 1.4% 5.0% ± 1.5%
2.0 mg/kg-bw 3.2% ± 1.4% 2.5% ± 0.86% 3.1% ± 1.1%
5.8 mg/kg-bw 5.0% ± 1.5% 1.3% ± 1.4% 1.2% ± 0.93%
NiO D 0.50 mg/kg-bw 2.4% ± 0.29% 3.7% ± 1.7% 2.5% ± 0.33%
1.6 mg/kg-bw 1.8% ± 0.61% 5.7% ± 1.1% 3.2% ± 0.68%
5.0 mg/kg-bw 2.0% ± 0.42% 2.7% ± 1.3% 4.8% ± 1.5%