Skip to main content

Advertisement

Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Fig. 6

TLR2 and TLR4 expression on the surface of primary bronchial epithelial cells (PBEC) and macrophages (MQ) after exposure to diesel exhaust particles (DEP). PBEC (A) and MQ (B) were identified by anti-CD 68-PE-Cy7. A representative mean fluorescence intensity (MFI) of 9 experiments is shown (A (a&b), B (a&b)); the expression of TLR2 (A (c)) and TLR4 (A (d)) on surface of PBEC in PBEC-ALI and PBEC-AL/MQ was presented as median and 25th -75th percentiles (N = 9); *, **: P < 0.05, 0.01 VS Sham exposure; ##: P < 0.01 VS PBEC-ALI. The expression of TLR2 (B (c)) and TLR4 (B (d)) on surface of MQ which have been co-cultured with PBEC was presented as median and 25th -75th percentiles (N = 9); *: P < 0.05 VS Sham exposure; Exposure: sham: clean air; DEP: 12.7 μg/cm2

Back to article page