Fig. 5From: Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activationEffects of NP on MAPK activation in the brain. Western blot analysis of various MAPKs in total protein lysates isolated from the frontal cortex and hippocampus (n = 8 for each group, except n = 7 for hippocampus control). Images show four representative protein bands. Band intensity was first normalized to that of α-tubulin. Phosphorylation was shown by phosphorylation form normalized to total form. Data was analyzed using unpaired Student’s t-tests. *p < 0.05, **p < 0.01, *** p < 0.001 compared to the controlBack to article page