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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation

Fig. 5

Effects of NP on MAPK activation in the brain. Western blot analysis of various MAPKs in total protein lysates isolated from the frontal cortex and hippocampus (n = 8 for each group, except n = 7 for hippocampus control). Images show four representative protein bands. Band intensity was first normalized to that of α-tubulin. Phosphorylation was shown by phosphorylation form normalized to total form. Data was analyzed using unpaired Student’s t-tests. *p < 0.05, **p < 0.01, *** p < 0.001 compared to the control

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