Skip to main content

Table 4 Quantification of dopaminergic and cholinergic inputs in GD28 olfactory tubercles

From: Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring

 

Control

Exposed

Effects of DE exposure

Effects of Sex

Exposure × Sex

Male (n = 4)

Female (n = 4)

Male (n = 8)

Female (n = 5)

F (1,16)

p-value

F (1,16)

p-value

F (1,16)

p-value

TH-labeling density (DO/surface unit, a.u)

21.27 ± 4.65

17.86 ± 4.84

15.89 ± 2.34

12.14 ± 4.11

2.461

0.143

1.080

0.319

0.001

0.980

AChe activity (μmol/min/g)

12.25 ± 0.34

9.21 ± 0.83

10.96 ± 0.85

10.66 ± 0.85

0.006

0.942

8.462

0.013*

5.773

0.033*

  1. Relative mean density of TH+ labeled fibers in the olfactory tubercle. The quantitative estimation did not show any significant difference between the two groups
  2. Relative mean density of AChE activity in the olfactory tubercle. There is no significant difference between the two groups regarding the DE exposure. However, we observed a sex-dependent difference between the two groups, which interacted significantly with DEP exposure. *p < 0.05
Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us