Fig. 2

Panel A: Alveolar-macrophage (AM) associated percentages of inhaled NP (20 + 80 nm iridium NP, 20 nm gold + elemental-carbon NP and 20 + 70 nm titanium dioxide NP) versus instilled micron-sized particles (0.5, 3, and 10 μm polystyrene (PSL) particles) found in bronchoalveolar lavage (BAL) of rats 24 h after application [54]. Panel B: Percentages of inhaled NP (20 nm iridium NP from 3 - 180 days and 20 nm gold + titanium dioxide NP from 3 - 28 days after inhalation) found in bronchoalveolar lavage fluids of rats at various time points [54] versus micron-sized particles (either inhaled 3.5 μm PSL [52] or intratracheally instilled fluorescent 2 μm PSL [51]. All percentages are relative to the contemporary lung burden.