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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm titanium dioxide nanoparticle aerosols in healthy adult rats after a single two-hour inhalation exposure

Fig. 5

Kinetics of [48V]TiO2-NP concentrations per weight of organ or tissue: (a): total translocation and blood, (b): liver, spleen, and kidneys, (c): heart, uterus, and brain, (d): carcass, skeleton, and soft tissue. The mean IPLD in mass (number) of [48V]TiO2-NP of all five retention time points is 1.01 ± 0.55 μg (2.67 ± 1.16•1010 #). Data are corrected for [48V]TiO2-NP retained in the residual blood volume of organs and tissues; data are presented as mean ± SEM; n = 4 rats per time point. Statistical one-way ANOVA analysis with the post-hoc Bonferoni test in between all time points are given in the table below:

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