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Table 2 Correlation between mortality recorded at day 18 and Ni/Co content or Ni/Co released by the particles

From: HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles

  Correlation coefficient p-value
Co content −0.064 0.801
Ni content 0.760 0.0002
Bioaccessible Co −0.079 0.755
Bioaccessible Ni 0.719 0.001
Ni + Co content 0.163 0.517
Bioaccessible Ni + Co 0.176 0.484
  1. Mice were treated with 0.5, 1 or 2 mg LIB particles (see Fig. 2). Bivariate analysis (Spearman Rho) between the mortality % at day 18, and the particle Ni and/or Co content (μg) or the amount of Ni and/or Co ions (μg) released. Co and/or Ni contents were calculated from the administered doses and from the Co and/or Ni % of the particles. Bioaccessible Co and/or Ni represent the amount of bioaccessible ions, calculated from the Co/Ni contained in the administered doses and the % released at pH 4.2 at day 14 (mortality was recorded between day 6 and 18). Significant relationships are identified in bold