Table 2 Summary of behavioral testing results
Behavioral measure | Results |
|---|---|
Locomotor Activity Testing | No change |
RAM: Spatial Learning | HUCAPS ↓ learning 3xTgAD ↓ learning rate |
RAM: Working Memory | 3xTgAD ↑ working memory error rate |
RAM: Reference Memory | HUCAPS ↑ reference memory errors |
NOR: Session 2 | HUCAPS & 3xTgAD impaired short-term memory |
Progressive Ratio Schedule | HUCAPS altered motivation in genotype-dependent manner |
Olfactory discrimination | Ratio-dependent 3xTgAD deficits in olfactory discrimination HUCAPS improved olfactory discrimination in NTg and worsened discrimination in 3xTgAD mice |