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Table 4 Absolute testes weight, daily sperm production (DSP) and serum testosterone concentration in Sprague Dawley rats

From: Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

 

Absolute testes weight (g)

DSP (107)

SC/Gtestes (× 107)

Week 12 – exposure

 Air + Reg

2.10 ± 0.2

1.39 ± 0.1

8.95 ± 1.2

 Air + HF

2.02 ± 0.2

1.36 ± 0.1

9.09 ± 0.9

 GMA-SS + Reg

2.06 ± 0.1

1.19 ± 0.2 ab

7.90 ± 0.7ab

 GMA-SS + HF

1.98 ± 0.2

1.23 ± 0.1 a

7.75 ± 0.8

Week 24 – recovery

 Air + Reg

2.29 ± 0.1

1.31 ± 0.7

3.50 ± 0.2

 Air + HF

2.15 ± 0.2

1.24 ± 0.2

3.51 ± 0.6

 GMA-SS + Reg

2.04 ± 0.2 a

1.18 ± 0.1

3.53 ± 0.1

 GMA-SS + HF

2.03 ± 0.1 a

1.14 ± 0.7

3.42 ± 0.2

  1. Absolute testes weight (g), daily sperm production (107) and sperm content per gram of testes in Sprague Dawley rats at week 12 after a 5-week exposure to 20 mg/m3 of GMA-SS, and at week 24 after a 12 week recovery period. Mean ± SD (n = 6–12). Significant effects are highlighted in bold
  2. aSignificantly different from Air+Reg diet (p < 0.05)
  3. bSignificantly different from Air+HF diet (p < 0.05)