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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

Fig. 2

Estimated TiO2 dose reaching the bottom of the wells after 24 h as a function of increasing nominal doses applied in exposure media. Dosimetry simulation was performed with a distorted grid (DG) model for 17 (a and c) and 117 nm (b and d) using parameters obtained from exposure media DMEM/F12 (a and b) and RPMI 1640 (c and d). The slope values are indicated near the respective lines. R2 > 0.99 for all the suspensions. The percentage of dose delivered to the cells did not differ for 96 and 24 well plates, as the height of the liquid column was similar (6 mm)

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