Fig. 6
Time-dependent gene expression of MMP-1 and MMP-9 on the apical and basolateral side of 3D tri-cultures after Si10 or Min-U-Sil exposure. The figure shows gene expression after 3, 6, 10 and 20 h exposure to 12 and 24 μg/cm2 Si10 (a-d) and 96 and 192 μg/cm2 Min-U-Sil (e-h). Gene expression was determined by qPCR and presented as fold increase compared to control. Data represent the mean +/− SEM of 3–5 independent experiments. *Statistical significantly difference from control at the same time-point, P < 0.05