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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO2 particles: an in vivo and ex vivo study in mice

Fig. 1

Analysis of TiO2 particle sizes. Size measurement of TiO2 particles detected in the intestinal lumen of jejunum or colon (lumen Jej and Col), in the jejunal villi and PP (Tissue Villi and PP), in the blood (B) and in the initial suspension (Suspension) before sonication (non-sonicated or NS) or after sonication (S). Confocal size measurement of the TiO2 particles was performed at high magnification with dual determination by confocal laser reflexion and by classic bright field observation. In addition, the latter S suspension was analysed by TEM (S MET), for comparison. Statistical significant difference between (a) Lumen Jej and Lumen col. (p < 0.001) and (b) in PP compared to B (p < 0.05), S and Lumen Jej (p < 0.001)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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