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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE−/− mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage

Fig. 9

ER stress involved in the lipid accumulation induced by SiNPs in RAW264.7 cells. a Representative lipid droplet staining images by Oil Red O staining. Scale bar = 20 μm. b The intracellular total cholesterol content of RAW264.7 cells. *p < 0.05 vs Control, #p < 0.05 vs SiNPs group with or without ox-LDL. Data are expressed as means ± SD of three independent experiments

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