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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method

Fig. 7

Diagram showing selected biological endpoints at 3 days (a) and 60 days (b) post-exposure to the different MWCNTs samples used in this study. Increasing distance away from the center indicates increasing biological response. In general, chemically purified MWCNTs and functionalized derivatives caused a greater increase in pro-inflammatory chemokines at 3 days post-exposure, while thermally purified MWCNTs and functionalized derivatives caused a greater increase in pro-fibrotic cytokines (OPN, CCL2) at 3 days and greater pulmonary toxicity (LDH, total protein), BAL lymphocytes, and numbers of granulomas at 60 days post-exposure

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Particle and Fibre Toxicology

ISSN: 1743-8977

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