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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Fig. 2

Exposure to DEP results in increased levels of immunoglobulins in the BALF. a Quantification of IgA (ng/ml) and b IgG (ng/ml), in the bronchoalveolar lavage fluid (BALF) of 4–6 week-old male C57Bl/6 wildtype mice, on either control (LF) or high-fat (HF) diet exposed to either saline (control) or diesel exhaust particles (DEP – 35 μg PM) twice a week for a total of 30 days, by ELISA. c Mean normalized gene expression of IgA receptor - pIgR and d IgG receptor – FcRn in lung tissues, as determined by RT-qPCR. Data are depicted as mean ± SEM with *p < 0.05 compared to LF Control, †p < 0.05 compared to HF Control, ‡p < 0.05 compared to LF DEP by two way ANOVA

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Particle and Fibre Toxicology

ISSN: 1743-8977

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