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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

Fig. 8

Intravitreal exposure of TiO2-NPs impaired the electrophysiology of retina. a ERG recordings were performed in dark room as described in Materials and Methods. Representative ERG α- and β-wave showed damages in their amplitude after TiO2-NP treatments (green and red lines), as compared to sham (black line). b Quantified data showed a great reduced amplitude of at day 7 (both α- and β-wave) and day 14 (α-wave); whereas β-wave amplitude seemed recovery at day 14. *p < 0.05, ***p < 0.001, indicates statistically significant difference from the control (day 0)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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